This lake stains the muscle cross striations, fibrin, nuclei, and other tissue elements blue.
2.
It is composed of tissue elements normally found at that site, but which are growing in a disorganized mass.
3.
The final step is the adhesion of the metastatic tumor cell to connective tissue elements such as fibronectin, type I collagen, and hyaluronan, which is required for the movement of the tumor cell into the subendothelial stroma and subsequent growth at the secondary site of colonization.